Titlebook: Strategies for Immunointerventions in Dermatology; Günter Burg (Chairman),Reinhard G. Dummer Book 1997 Springer-Verlag Berlin Heidelberg 1

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Skin as an Immunocompetent Organ in Health and Disease cold, own and foreign, thus enabling us to keep all of our body systems in working order. Here, at the very border of our entire organism, the immunologic properties of the skin, our largest organ, are of vital importance. In addition to its well-known physical protective properties, human skin is

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FK-506/Tacrolimusillin,it was no accidential finding but the result of a thoroughly undertaken screening project for new immunomodulatory substance by researchers of a an industrial company.Following 3 years of extensive research, the first report on this new drug was published by Kino et al. [1]. The newly identifi

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Leflunomidee is rapidly absorbed and converted, by opening the isoxazole ring, to the active metabolite A77 1726 (Fig. 1). This new drug has shown efficacy in an array of animal models of autoimmune disease [1–4,11,22,25,27,30] and organ graft rejection [4,14,17,24,29,32]. It has also demonstrated efficacy and

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Dermatological Phototherapy: A Prime Example of Ultraviolet Radiation-Induced Immunointerventionr of ultraviolet (UV) radiation, on the immune system. Interest in photoimmunology originated from observations made in three different research fields: (1) photocarcinogenesis, (2) studies on the function of epidermal Langerhans cells, and (3) the increasing use of UV radiation for the treatment of

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