Titlebook: Stochastic Decomposition; A Statistical Method Julia L. Higle,Suvrajeet Sen Book 1996 Springer Science+Business Media Dordrecht 1996 Mathem

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Julia L. Higle,Suvrajeet Senexemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease.

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Julia L. Higle,Suvrajeet Seneavy metal, nutrient deficiency and UV radiation. Such types of stresses in plants lead the overproduction of certain chemical entities known as reactive oxygen species (ROS) which are highly reactive and cause damage to proteins, lipids, carbohydrates and macromolecules. The ROS include hydrogen pe

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Julia L. Higle,Suvrajeet Senen species (ROS) like superoxide (O..), hydroxyl radical (.OH), and hydrogen peroxide (H.O.), during the course of normal metabolic reactions. If it is not effectively and rapidly removed, ROS damages a wide range of macromolecules, ultimately leading to cell death. ROS are also generated in respons

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Julia L. Higle,Suvrajeet Sening atmospheric UV radiation (solar zenith angle, ozone column amount, clouds and aerosols, surface reflections) are fairly well understood in principle, but usually at least some of these are not known for an arbitrary location and time of interest. Reductions in stratospheric ozone have so far cau

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f aging such as cancer,cardiovascular disease,cataracts,and brain dysfunction are increasingly found to have,in good part,an oxidative origin (Ames .,1993). Much evidence is available to support the notion that dietary antioxidants such as vitamins C,E,and the carotenoids play a major role in minimi