书目名称 | Stereoselective Heterocycle Synthesis via Alkene Difunctionalization |
副标题 | Bulky Phosphine Liga |
编辑 | David A. Petrone |
视频video | |
概述 | Nominated as an outstanding Ph.D. thesis by the University of Toronto, Canada.Includes extensive background literature on Pd-catalyzed cross-coupling chemistry and catalytic carbon–halogen bond format |
丛书名称 | Springer Theses |
图书封面 |  |
描述 | This book investigates the use of palladium modified by bulky ligands as catalysts for new chemical transformations that rapidly assemble several classes of complex heterocyles. It documents the development of new chemical reactions involving carbon–carbon (C‒C) and carbon–halogen (C‒X) bond formation in the context of alkene difunctionalization and dearomatization reactions. Due to the ubiquity of heterocycles in bioactive natural products and life-improving pharmaceutical treatments, a long-term goal for synthetic organic chemists has been to develop novel and creative heterocycle syntheses that illicit a high degree of product diversity and are characterized by mild reaction conditions and limited waste production. A considerable fraction of leading pharmaceutical drugs contain at least one heterocycle within their chemical structure, and their prevalence in these technologies is strong evidence that the fundamental curiosities of organic chemistry lead to real-world solutions for the health and wellness of the global population.. |
出版日期 | Book 2018 |
关键词 | Palladium Catalysis; Stereoselective Synthesis; Catalyst Development; Halogenation Reactions; Suzuki Cou |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-77507-4 |
isbn_softcover | 978-3-030-08472-1 |
isbn_ebook | 978-3-319-77507-4Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
issn_series | 2190-5053 |
copyright | Springer International Publishing AG, part of Springer Nature 2018 |