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Titlebook: Stem Cells and Their Potential for Clinical Application; Nadja M. Bilko,Boris Fehse,Axel R. Zander Conference proceedings 2008 Springer Sc

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Alterations of Frequency of Hematopoietic Precursors in Mice Subjected to Multiple Courses of Low-Dotem cells (LTC-IC) decreased one month after the last (7th) course of G-CSF injections, moreover it halved during the following year. The exhaustion of LTC-IC after G-CSF treatment is discussed..Keywords: granulocyte colony-stimulating factor (G-CSF); LTC-IC; CFU-C; granulocytes
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Regulation of Hematopoiesis by Growth Factors-1 (CSF-1), is reviewed, including its function in development as revealed by studies of mouse mutants and its role in innate immunity, inflammatory disease and cancer..Keywords: blood cells, macrophages, osteoclasts, review, CSF-1
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Novel Methodological Approaches in Assessment and Enrichment of Stem Cell Populationd by stromal cells are sufficient for the regeneration of primitive hematopoietic cells, or whether direct cell-to-cell contacts would be required..Keywords: stem cell expansion; stem cell culture .; diffusion chambers
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Clonal Dominance after Reconstitution of the Haematopoietic System with Bone Marrow Cells Retroviral marrow stem cells we found insertions into genes shown to be involved in cell cycle regulation and stem cell self-renewal such as a Core-binding factor α group member (Cbfα2t3h), runt-related Runx3, Ras p21 protein activator 4 (RasA4), Hematopoietically expressed homeobox (Hhex) or FBJ Osteosarcoma
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Function of the Membrane-Bound Isoform Ligands of the Receptor Tyrosine Kinase Subclass III in Inducress the different isoforms. In cocultures of SCF- or CSF-1 transduced epithelial cells with primary early hematopoietic progenitor cells we examined whether interaction between the membrane-bound isoforms of SCF and CSF-1 and their receptors mediate cell proliferation, self-renewal or differentiati
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Epithelial Plasticity of Hepatocytes During Liver Tumor Progressionof platelet-derived growth factor (PDGF) links TGF-β signaling to nuclear β-catenin accumulation upon EMT. PDGF-dependent activation of β- catenin reduces cellular turnover and provides protection of malignant hepatocytes against anoikis, the latter known as a prerequisite for dissemination of carci
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