Titlebook: Stem Cell and Gene-Based Therapy; Frontiers in Regener Alexander Battler,Jonathan Leor Book 2006 Springer-Verlag London 2006 Cardiac regene

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Renovation of the Injured Heart with Myocardial Tissue Engineeringis to generate significant mass of functional heart muscle tissue. However, the area of myocardial tissue engineering still faces significant difficulties. Scientists are still searching for cell types other than cardiomyocytes. Novel approaches are warranted for material processing to create bioact

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Regeneration of the Functional Myocardium Using Human Embryonic Stem Cells fields. Research based on the cells may help to elucidate the mechanisms involved in early human cardiac lineage commitment, differentiation, and maturation. Moreover, this research may promote the discovery of novel growth and transcriptional factors using gene trapping techniques, functional geno

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Therapeutic Angiogenesisesults of several phase II studies raise concerns regarding the potential of the single growth factor approach. Administration of BM cells and peripheral blood-derived mononuclear and progenitor cells is a novel therapeutic strategy derived from the hypothesis that meaningful therapeutic angiogenesi

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Cell Therapy for Heart Failurey contractile tissue, thereby completely restoring cardiac pumping capacity, have not yet been accomplished, many experimental studies reported beneficial effects on left ventricular performance, most of them attributed to less ventricular dilation, scar thickening, and reduction of infarct expansio

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Cell Transplantation for Diseases of Myelinransplantation of exogenous cells, as an alternative source of remyelinating cells, has been pursued as a very active research area over the last decade and remarkable progress has been obtained. New sources of myelinating cells were characterized and different transplantation strategies have been p

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