Titlebook: Stem Cell Therapy for Vascular Diseases; State of the Evidenc Tulio Pinho Navarro,Lara Lellis Navarro Minchillo Book 2021 Springer Nature

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Bone Marrow-Derived Cells: From the Laboratory to the Clinic,al models of CLI in which mechanisms of bone marrow-derived cells were investigated. Finally, the progress in the clinical trials using BMMNC to treat CLI patients were summarized, and the challenges were discussed.

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Venous Foot and Leg Ulcers,about their benefit in venous wounds. Further research is also necessary to better define the ideal stem cell type, source, and method of delivery in order to maximize their therapeutic potential. Larger clinical trials will be necessary to prove their efficacy and safety in all types of wound repair.

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,Mesenchymal Stem Cell and Endothelial Progenitor Cell Transplantation for Buerger’s Disease,ge randomized, placebo-controlled, double-blind studies involving homogenous patient populations are necessary to provide stronger safety and efficacy data on cell therapy. In addition, many challenges still exist, including optimization of cell types, dosing, and frequency of application.

Maximizer

Stem Cell Therapy Delivery in Liver Disease,r’s natural repair processes. However, realizing this potential will require addressing three key challenges delineated in this chapter: (1) identifying the most effective stem cell type(s), (2) determining the impact of liver disease etiology, and (3) optimization of route and timing of delivery to ensure maximal therapeutic benefit.

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Use of Stem Cells in the Treatment of Erectile Dysfunction,s paracrine effects to immunomodulate through secretion of cytokines and growth factors. We herein review the published data regarding effects of stem cells on erectile dysfunction and comment on the current state of clinical use/overuse of this treatment at the present time.