Titlebook: Stem Cell Surgery Trials in Heart Failure and Diabetes; A Concise Guide Jeffrey N. Weiss Book 2022 The Editor(s) (if applicable) and The Au

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ICMNC-HF: IntraCoronary Bone Marrow MonoNuclear Cells in Heart Failure (HF) Patientsinfusion of autologous bone marrow mononuclear cells is safe and effective in heart failure patients with reduced left ventricular ejection fraction (<=30%) when compared with a control group comprising of patients undergoing the best medical care.

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Efficacy and Safety of Allogeneic Mesenchymal Precursor Cells (Rexlemestrocel-L) for the Treatment oThe primary objective of this study is to determine whether transendocardial delivery of allogeneic human bone marrow-derived MPCs (rexlemestrocel-L) is effective in the treatment of chronic heart failure due to LV systolic dysfunction.

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Allogeneic Stem Cell Therapy in Heart FailureThe present aim is to perform a clinical double-blind, placebo-controlled Cardiology Stem Cell Center – Adipose Stem Cells (CSCC_ASC) study in heart failure patients to investigate the regenerative capacity of the CSCC_ASC treatment.

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Stem Cell Therapy in Ischemic Non-treatable Cardiac DiseaseThe aim of the SCIENCE study, an international multicenter, double-blind, placebo-controlled study, is to investigate the efficacy of direct intra-myocardial injection of 100 mio. allogeneic Cardiology Stem Cell Center adipose-derived stem cells (CSCC_ASCs) in patients with reduced left ventricular ejection fraction (EF) (≤45%) and heart failure.

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Cell Therapy in HFpEFThe primary objective of the study is to investigate the safety and efficacy of transendocardial CD34+ cell therapy in patients with HFpEF by evaluating changes in myocardial structure and function, myocardial perfusion and electrical activity, biomarkers of neurohormonal activation, patient exercise capacity, and clinical outcome.

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Compare the Effects of Single Versus Repeated Intracoronary Application of Autologous Bone Marrow-DeSingle or repeated application of autologous bone marrow-derived stem cells to treat chronic post-infarction heart failure

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Stem Cell Therapy in Non-ischemic, Non-treatable Dilated Cardiomyopathies II: A Pilot StudyThe overall aim of the project is to test the feasibility and safety of allogeneic adipose-derived stromal cell (CSCC_ASC) investigational medicinal product to improve myocardial function in patients with non-ischemic dilated cardiomyopathies (NIDCM) and heart failure.

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Jeffrey N. WeissFunctions as a resource for new treatments for patients with heart failure and diabetes mellitus.Offers comprehensive information for physicians interested in stem cell technology.Provides a template

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