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Titlebook: Starling’s Law of The Heart Revisited; H. E. D. J. Keurs,M. I. M. Noble Book 1988 Kluwer Academic Publishers 1988 heart

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书目名称Starling’s Law of The Heart Revisited
编辑H. E. D. J. Keurs,M. I. M. Noble
视频video
丛书名称Developments in Cardiovascular Medicine
图书封面Titlebook: Starling’s Law of The Heart Revisited;  H. E. D. J. Keurs,M. I. M. Noble Book 1988 Kluwer Academic Publishers 1988 heart
描述H. E. D. J. TER KEURS & M. I. M. NOBLE The "Starling‘s Law of the Heart" and "The Frank-Starling Mechanism" have long been the cornerstone of cardiac mechanical physiology. It is often forgotten that Frank and Starling carried out fundamentally different exper­ iments. Frankl measured the isovolumic pressure developed by frog heart at different volumes. He therefore discovered the pressure-volume-volume rela­ tionship which depends directly on the force-length relationship of the 2 sarcomeres. Starling ,3 studied cardiac shortening as manifest by cardiac output and its relationship to end-diastolic conditions as manifest by right atrial pressure. Thus he was studying the ability of cardiac muscle to shorten more at a given load from a greater initial length. Starling in the promulga­ 4 tions of his law implied a common mechanism for these two phenomena and spoke of the "energy liberated" being a function of initial muscle fiber length. However, there has been much confusion about the interrelationship between the two different aspects studied by Frank and Starling. The 1960s saw the era of isolated cardiac muscle mechanics, beginning with 5 the paper of Abbott and Mommaerts. Whole
出版日期Book 1988
关键词heart
版次1
doihttps://doi.org/10.1007/978-94-009-1313-4
isbn_softcover978-94-010-7084-3
isbn_ebook978-94-009-1313-4Series ISSN 0166-9842
issn_series 0166-9842
copyrightKluwer Academic Publishers 1988
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Similarity and Dissimilarity Between Muscle Force-Length Relationship and Ventricular Pressure-Voluening induced deactivation factor in addition. The effect of contractility on the shape of the force-length relationship was also found in the end-systolic pressure-volume relation of the left ventricle. Low contractility (extrasystoles) gave curves convex towards the volume axis; high contractility
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The Importance of the Geometry of the Heart to the Pump,ually applicable to mice and elephants and gives realistic ventricular haemodynamic and muscle mechanical values. It can also accommodate the right ventricle, valves, chordae tendinae and papillary muscles.
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