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Titlebook: Spirochete Biology: The Post Genomic Era; Ben Adler Book 2018 Springer International Publishing AG, part of Springer Nature 2018 Lyme dise

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Erratum to: Gene Regulation, Two Component Regulatory Systems, and Adaptive Responses in ,
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Gene Regulation, Two Component Regulatory Systems, and Adaptive Responses in ,mplex. Of the ~400 bacterial species identified in subgingival plaque, at least 50 belong to the genus .. As periodontal disease develops and progresses, . transitions from a low to high abundance species in the subgingival crevice. Changes in the overall composition of the bacterial population trig
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Physiologic and Genetic Factors Influencing the Zoonotic Cycle of ,ch, in turn, act as reservoirs for naïve ticks to become infected, perpetuating the infectious life cycle of .. The pivotal role of ticks in this life cycle and tick–spirochete interactions are the focus of this chapter. Here, we describe the challenging physiological environment that spirochetes en
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Genetic Manipulation of , Spp., a vertebrate host. They have extraordinarily unusual genomes that are highly segmented and predominantly linear. The genetic analyses of Lyme disease spirochetes have become increasingly more sophisticated, while the age of genetic investigation in the relapsing fever spirochetes is just dawning. M
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Leptospiral Genomics and Pathogenesis,l genome sequence in 2003 was followed rapidly by other whole genome sequences, whose availability facilitated the development of transposon mutagenesis and then directed mutagenesis of pathogenic . spp. The combination of genomics, transcriptomics and mutant construction and characterisation has re
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Complement Immune Evasion by Spirochetes,regulating proteins allows the distinction between intact and damaged host and non-host surfaces such as bacteria and other parasites. Non-host structures trigger the alternative pathway which may lead to their elimination by phagocytosis or cell lysis. In addition, complement proteins such as C1q,
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