Titlebook: Spermatogenesis — Fertilization — Contraception; Molecular, Cellular Eberhard Nieschlag,Ursula-F. Habenicht Conference proceedings 1992 Sp

六个才偏离

Structure and Function of the Human Androgen Receptor,ndrogenic hormones (e.g. testosterone and 5αdihydrotestosterone) is mediated by the intracellular androgen receptor, which belongs to a superfamily of ligand-dependent transcription factors. This family also includes the other steroid hormone receptors and the thyroid hormone and retinoic acid receptor subfamilies (Evans 1988; O’Malley 1990).

有角

Cell Surface Actions of Steroids: A Complementary Mechanism for Regulation of Spermatogenesis?,ysiological conditions androgen concentrations in the testis are more than 20-fold higher than in peripheral organs. However, results of various studies show that spermatogenesis can also proceed at approximately 20% of the normal testicular an-drogen level although the production of spermatozoa is

breadth

Essential

Development of Antagonists and Agonists of Follicle Stimulating Hormone,n species, it is clear that FSH is an important regulator, in particular during the first wave of spermatogenesis, and that testosterone is the major stimulator of spermatogenesis in adult males. FSH exerts multiple effects on its target cell, the Sertoli cell, and its action is most evident in test

菊花

意外

Structure and Function of the Human Androgen Receptor,velopment and maintenance of secondary male characteristics, feedback regulation of gonadotrophin secretion](Griffin and Wilson 1989). The action of androgenic hormones (e.g. testosterone and 5αdihydrotestosterone) is mediated by the intracellular androgen receptor, which belongs to a superfamily of

流逝

Androgens and the Brain: Role of Testosterone Metabolism,, estrogens, progesterone, and corticoids have been shown to be present in several brain regions (Martini 1978). The CNS also represents an area of intense metabolism of steroid hormones. The study of the metabolism of androgens, and especially of testosterone, has been the subject of particularly a

责任

The Ovarian and Testicular IGF-I System: A Comparative Analysis,(IGFs). Indeed, a large body of evidence now suggests the existence of an intraovarian IGF system complete with ligands, re-ceptors, and binding proteins (Adashi et al. 1985c). More importantly, IGFs have been shown to exert a variety of significant effects in murine (Adashi et al. 1985a,b,d; 1986b;

insidious

结合

Expression of Proto-Oncogenes and Protein Kinases in the Testis,y are expressed. A molecular genetic approach to understanding the control of male germ cell differentiation involves, in part, identifying genes that are expressed in a spermatogenic cell type-specific manner. Previous observations from our laboratory and others have shown that some testis-specific