Titlebook: Specificity and Function of Clonally Developing T Cells; Bernhard Fleischer,Jörg Reimann,Hermann Wagner Conference proceedings 1986 The Ed

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The Change of Specificity, Karyotype, and Antigen-Receptor Gene Expression is Correlated in Cytotoxiat physiological potential the cells either degenerate or transform malignantly. Long-term cultured T-cell clones are intriguing models to test the above postulate. Because of that model character, the karyotypic and molecular genetic analysis of cytotoxic lymphocyte clones (CTLL) and their variants

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Introductory Remarksolate to the in vivo significance. The function of T cells can only be measured after their activation. There is no single-cell assay for most T-cell functions. Consequently the function of the progeny of a single cell is being analyzed. This, however, puts constraints on the validity of the analysi

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A Study of the Functional Potential of Mouse T-Cell Clonesvely homogeneous cells, has provided a powerful tool for analysing the biology and bio-chemistry of T-lymphocyte function. Cloned T-cell lines have played a central role in the acquisition of knowledge of the T-cell antigen receptor and have provided new insights into the recognitive and functional

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Significance of T4 or T8 Phenotype of Human Cytotoxic T-Lymphocyte Clonesbasis of cell separation experiments, the helper function for.or T lymphocytes, the proliferative capacity to soluble antigens (tuberculin, tetanus toxoid) and to alloantigens has been assigned to the T4/Leu 3 subset, while cytotoxic and suppressor functions are associated with the T8/Leu 2 subset (

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