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Titlebook: Special Problems in Chemotherapy; J. D. Williams,A. M. Geddes Book 1976 Springer Science+Business Media New York 1976 cancer.chemotherapy.

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Singapore Study of Intermittent Rifampicin Plus Isoniazid for Pulmonary Tuberculosis, isoniazid. All patients received an initial two weeks of daily chemotherapy with streptomycin plus isoniazid plus rifampicin in standard daily dosages, followed by isoniazid 15 mg/kg body weight plus rifampicin 900 mg, both drugs twice a week (HR2 regimen) or once a week (HR1 regimen), or by isonia
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Short-Course Chemotherapy in Pulmonary Tuberculosis,e learnt how best to deploy them. As a result of a mixture of clinical experience and well-planned controlled clinical trials, we learnt that the use of any single agent alone would lead to a substantial proportion of treatment failures due to the development of bacteriological resistance. This prob
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Structure-Activity Study on the Kasugamycin Family,udies showed that MSM inhibits protein synthesis in mycobacteria. MSM, at 2×10.M, also inhibits f. RNA-directed protein synthesis in an . cell-free system by 50%. This inhibition is 100 times stronger than that caused by KSM in the same system. Like KSM, MSM preferentially inhibits the initiation pr
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Experimental Data on the Antimycobacterial Activity of Isoprodian(R),d more or less separately, in spite of the obvious advantage of a common approach recognized e.g. by Mayer (1964) or possibly even earlier. Prothionamide (PTH) and/or diaphenylsulphone (DDS) were claimed to increase the antimycobacterial activity of rifampicin (RMP, Freerksen and Rosenfeld, 1972) or
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Rate of Sterilization of Sputum from Patients with Pulmonary Tuberculosis, sputum of patients with pulmonary tuber­culosis, the number of culturable mycobacterial cell units per ml. of sputum was determined in 28 patients before and during chemo­therapy. The data obtained clearly showed, perhaps for the first time, that there is a very significant decrease in the acid-fas
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Incidence of Drug Resistance on the Mycobacterial Strains Isolated from Treated and Untreated Patiegs. Two hundred and ninety-four of the strains were identified as ., and fourteen as atypical mycobacteria. All strains were of human origin..The strains of . isolated from untreated patients (110 strains) were sensitive to Rifampicin and Ethambutol, while those isolated from treated patients showed
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