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Titlebook: Spanlose Fertigung: Schneiden — Biegen — Ziehen; Erwin Semlinger,Waldemar Hellwig Textbook 1990Latest edition Friedr. Vieweg & Sohn Verlag

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Erwin Semlinger,Waldemar Hellwigs system which appear to function as neurotransmitter agents. Recently, electro physiological and biochemical methods have been developed which have enabled neuroscientists to classify better the myriad of neurotransmitter receptor sites in brain and to study their properties in finer detail. As a r
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Erwin Semlinger,Waldemar Hellwig constricts both vascular and non-vascular smooth muscle, stimulates gastric secretions, increases capillary permeability, and has both inotropic and chronotropic effects on the heart (Beavan, 1976a, b; Douglas, 1975). The principle cellular storage sites for histamine are mast cells and basophils.
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Erwin Semlinger,Waldemar Hellwig efforts of several neurophysiologic laboratories, evidence has accrued that glutamic acid and possibly aspartic acid may serve as excitatory neurotransmitters in the mammalian central nervous system (Curtis .., 1972; Curtis and Johnston, 1974; Krnjevic, 1974; McLennan, 1975). Prompted by these neur
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Erwin Semlinger,Waldemar Hellwigtrue for the opiate narcotics, which exert their principal effects by interacting with receptors whose endogenous ligands are opioid peptides such as enkephalin and .-endorphin. This conclusion has been obtained by two general advances of research. The first, in 1973, was the finding that labeled op
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Erwin Semlinger,Waldemar Hellwigral properties of psychostimulants for nearly three decades. The primary means by which dopamine transmission in the synapse is terminated is via the dopamine transporter (DAT), the presynaptic plasmalemmal protein that is responsible for the reuptake of released dopamine. Numerous abused as well as
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Erwin Semlinger,Waldemar Hellwigstored, released, metabolized, and recaptured determines the intensity of monoaminergic signaling (.). Released monoamines undergo enzymatic degradation and dilution by diffusion; however, a major mechanism in the control of extracellular monoamine dynamics is selective uptake by presynaptic neurons
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d stimulant drugs. As a means to identify novel medications for stimulant addiction and other psychiatric disorders, we developed in vitro assays in rat brain tissue that can be used to determine structure–activity relationships for test compounds at these monoamine transporters. Uptake inhibition a
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