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Titlebook: Soft Tissue Sarcomas in Adults; M. Bamberg,W. Hoffmann,D. K. Hossfeld Conference proceedings 1995 Springer-Verlag Berlin Heidelberg 1995 G

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Histomorphological Characteristics of Metastases of Soft Tissue Sarcomass develop during the course of the disease, either via the blood stream or through the lymphatics. Once metastases have occurred, the prognosis becomes very poor despite the availability of multimodality treatment with surgery, radiation, and chemotherapy. The probability of metastatic spread is det
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Adjuvant Chemotherapy of Soft Tissue Sarcomas in North Americar chemotherapy adds to surgery and radiation in the management of patients with soft-tissue sarcomas and whether adjuvant chemotherapy is indicated in the management of patients with soft tissue sarcomas. This manuscript is intended to demonstrate that the answer to these questions is yes, but that
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Systemic Therapy of Disseminated Soft Tissue Sarcomasrgical resection is either not possible or not indicated, systemic chemotherapy remains the sole treatment option. Unfortunately, very few active drugs are available in metastatic STS. Only doxorubicin, ifosfamide, and dacarbazine (DTIC) result in remission rates greater than 15%.
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Isolation Perfusion with Tumor Necrosis Factor-α, Interferon-γ, and Hyperthermia in the Treatment ofsequence which is highly conserved among numerous species (Spriggs 1991). TNF-α was initially described as an agent causing hemorrhagic necrosis of transplanted murine sarcomas and as a protein associated with chronic wasting disorders and sepsis (cachectin). These two functions were found to be cau
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Immunohistochemistry in Diagnosis of Soft Tissue Sarcomas and New Techniques in Soft Tissue Tumour P technique is characterised by the application of antibodies, either monoclonal or polyclonal, to tissue sections in order to detect antigens in a given tumour. Various methods may be employed, but the most popular, at present, is probably the avidin—biotin—peroxidase complex (ABC) method.
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Radiotherapy in the Treatment of Inoperable and Advanced Soft Tissue Sarcomas in Adultsowed by intensive radiotherapy depending on size, localization, and grading of the tumor. In inoperable disease irradiation as radical treatment seems to be unrealistic, because the goals of treatment to render the patient free of tumor and to produce no morbidity can hardly be achieved (Bamberg et al. 1989; Fig. 1).
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Histomorphological Characteristics of Metastases of Soft Tissue Sarcomass very poor despite the availability of multimodality treatment with surgery, radiation, and chemotherapy. The probability of metastatic spread is determined by several factors. Among these are tumor site, tumor size, histological subtype, grade, and type of therapy.
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