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Titlebook: Sodium Channels, Pain, and Analgesia; Michael J. Parnham (Senior Scientific Advisor),Kev Book 2005 Birkhäuser Basel 2005 Nervous System.So

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发表于 2025-3-21 17:28:06 | 显示全部楼层 |阅读模式
书目名称Sodium Channels, Pain, and Analgesia
编辑Michael J. Parnham (Senior Scientific Advisor),Kev
视频video
概述Written by well-known scientists in their respective fields.The Nav1.8 sodium channel is discussed.Provides current opinion and future direction.Includes supplementary material:
丛书名称Progress in Inflammation Research
图书封面Titlebook: Sodium Channels, Pain, and Analgesia;  Michael J. Parnham (Senior Scientific Advisor),Kev Book 2005 Birkhäuser Basel 2005 Nervous System.So
描述.Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially important drug targets in the treatment of pain. The roles of sodium channels in dental and visceral pain are also addressed. The emerging role of sodium channel Nav1.3 in neuropathic states is another important theme. ..Authors from the pharmaceutical industry discuss pharmacological approaches to the drug targeting of sodium channels, and in particular Nav1.8, exclusively expressed in nociceptive neurons. The final chapter highlights the functional diversity of sodium channels in part provided by post-transcriptional processing and the insights into sodium channel function that are being provided by tissue specific and inducible gene knock-out technology..
出版日期Book 2005
关键词Nervous System; Sodium channels; analgesics; brain; drug; gene; membrane; neurons; pain; protein; proteins; res
版次1
doihttps://doi.org/10.1007/3-7643-7411-X
isbn_ebook978-3-7643-7411-2Series ISSN 1422-7746 Series E-ISSN 2296-4525
issn_series 1422-7746
copyrightBirkhäuser Basel 2005
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发表于 2025-3-21 20:40:47 | 显示全部楼层
Sodium Channels, Pain, and Analgesia978-3-7643-7411-2Series ISSN 1422-7746 Series E-ISSN 2296-4525
发表于 2025-3-22 03:50:13 | 显示全部楼层
Michael J. Parnham (Senior Scientific Advisor),KevWritten by well-known scientists in their respective fields.The Nav1.8 sodium channel is discussed.Provides current opinion and future direction.Includes supplementary material:
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Progress in Inflammation Researchhttp://image.papertrans.cn/s/image/870395.jpg
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Future directions in sodium channel research, all may amplify the repertoire of voltage-gated sodium channels. Using adult inducible knockouts of the various components of sodium channel complexes should provide invaluable information for defining new targets for therapeutic intervention in a much more efficient way than conventional pharmacology allows.
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