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Titlebook: Sleep and its Disorders; Translational Medici Allan I. Pack,Qing Yun Li Book 2022 Springer Nature B.V. and Shanghai Jiao Tong University Pr

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Circadian Rhythm Sleep–Wake Disorders: Mechanisms and Treatmental circadian clock, the suprachiasmatic nucleus helps to align behaviors and physiological processes, including the sleep–wake cycle with the 24-h environment. Disruption of the proper alignment of circadian clocks with the required sleep–wake time leads to development of circadian rhythm sleep–wake
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Book 2022is on advancing basic science into clinical medicine. It is divided into three main parts. The first part is to cover the basic sleep mechanisms which includes genetics in sleep, and neural and humoral regulation of sleep and wakefulness. The second part focuses on the epidemiology of sleep, and the
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Sleep Loss and the Unfolded Protein Responses the degree of sleep recovery following sleep deprivation. Moreover, administration of drugs that alter the UPR can reduce the sleep fragmentation that occurs with age. UPR response to sleep loss has implications for neurodegenerative disorders and other medical conditions.
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Biological and Genetic Mechanisms of Sleepiness in Obstructive Sleep Apnea and Cardiovascular Diseas As the mechanisms of excessive daytime sleepiness associated with obstructive sleep apnea and how this plays a role in cardiovascular disease risk is unknown, exploring the potential mechanisms will be an important avenue to guide treatment options based on data from the molecular level.
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Diaphragm EMG Recording and Its Application in Sleep Medicine to further understand the mechanism of pathophysiological changes in patients with OSA including those with both OSA and chronic obstructive pulmonary disease (COPD), overlap syndrome. Assessment of diaphragm EMG can also be used to differentiate central from obstructive sleep apneas.
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