| 书目名称 | Site-directed insertion of transgenes | | 编辑 | Sylvaine Renault,Philippe Duchateau | | 视频video | http://file.papertrans.cn/869/868076/868076.mp4 | | 概述 | No other book published in this field of research.Presentation of all the innovative methodologies in genome engineering.From basic science to practical applications.Concerns a broad range of organism | | 丛书名称 | Topics in Current Genetics | | 图书封面 |  | | 描述 | The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strategies. Genomic modifications such as knock-in, knock-out, knock-down, sequence replacement or modification can today be routinely performed. However, in front of this large palette of methodologies scientists may experience difficulties to gather useful information’s scattered within the literature. This book aims to present the state of this field from basic mechanisms of site-directed modifications to their applications in a wide range of organisms such as bacteria, yeast, plants, insects, mammals. It will discuss the problems encountered when using the random integration strategy and present the recent advances made in targeted genome modification. Technologies based on Zinc Finger nucleases, Meganucleases, TALEN, CRE and FLP recombinase, C31 integrase, transposases and resolvases are fully detailed with their strengths and weaknesses. All these information’s will help students and experienced researchers to understand and choose the | | 出版日期 | Book 2013 | | 关键词 | genome engineering; homologous recombination; site-specific recombination; targeted genome modification | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-007-4531-5 | | isbn_softcover | 978-94-017-8075-9 | | isbn_ebook | 978-94-007-4531-5Series ISSN 1610-2096 Series E-ISSN 1610-6970 | | issn_series | 1610-2096 | | copyright | Springer Science+Business Media Dordrecht 2013 |
The information of publication is updating
|
|
|Archiver|手机版|小黑屋|
派博传思国际
( 京公网安备110108008328)
GMT+8, 2025-8-7 23:04
发表于 2025-3-21 18:34:47
