Titlebook: Single-Cell Mutation Monitoring Systems; Methodologies and Ap Aftab A. Ansari,Frederick J. Serres Book 1984 Plenum Press, New York 1984 Fix

果核

Detection of Chemically Induced Y-Chromosomal Nondisjunction in Human Spermatozoa, presumably the number of investigators evaluating this technique are minimal. In this chapter, we will describe the studies that led to the development of this method, discuss the technique, and present data obtained using this procedure.

含水层

Book 1984 injury requires monitoring the exposed individuals for genetic damage and identifying chemicals that may cause mutation or cancer. Tests available for identifying mutagens or carcinogens range from relatively simple, rapid assays in prokaryotes and test systems utilizing mammalian cells in tissue c

TAIN

创新

The Identification of Somatic Mutations in Immunoglobulin Expression and Structure,time of animal cells has made it more difficult to establish useful genetic systems, the very complexity of such cells demands that molecular genetics be used if we are ever to fully understand how they function.

Thyroid-Gland

Somatic-Cell Mutation Monitoring System Based on Human Hemoglobin Mutants,ozygous for an abnormal hemoglobin. It is assumed, first, that mutations arise spontaneously in human hemopoietic stem cells, as they do in gametal stem cells, and second, that somatic mutations of globin-chain genes do not diminish the viability of affected stem cells. The latter assumption is a re

ASSET

laparoscopy

Development of a Plaque Assay for the Detection of Red Blood Cells Carrying Abnormal or Mutant Hemoen) has been recently reviewed.. The use of immunological methods for detection of mutations has been possible by using antibodies that can specifically recognize the amino acid difference(s) between the molecule normally present in a given cell and its variant form. Techniques like immunofluorescen

嬉耍

acrophobia

Application of Antibodies to 5-Bromodeoxyuridine for the Detection of Cells of Rare Genotype, The primary purpose of automating mutagen detection is to increase the speed and statistical reliability that is afforded by the instrumentation being recruited to this task, flow or image cytometry. In addition, this approach would eliminate the human bias and error characteristic of manual method

致命

Cytogenetic Abnormalities as an Indicator of Mutagenic Exposure,t to cycle. In animals there are several cell types that fit these criteria, but for humans there are to all intents and purposes only two types that are practically suitable. These are the bone marrow cells, which are a cycling population, and peripheral lymphocytes, which are normally noncycling,