书目名称 | Single Nucleotide Polymorphisms | 副标题 | Methods and Protocol | 编辑 | Anton A. Komar | 视频video | | 概述 | Fully updated from the first edition to offer cutting-edge methods for SNP detection and analysis.Offers a unique overview of next generation sequencing and genotyping approaches.Contains review chapt | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In .Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition., expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful .Methods in Molecular Biology.™ series format, each chapter contains a brief introduction, step | 出版日期 | Book 2009Latest edition | 关键词 | Advanced genome sequencing; Allele; DNA; DNA sequencing; Direct SNP detection; Indirect SNP detection; Iso | 版次 | 2 | doi | https://doi.org/10.1007/978-1-60327-411-1 | isbn_softcover | 978-1-61779-679-1 | isbn_ebook | 978-1-60327-411-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Humana Press 2009 |
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