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Titlebook: Single Nucleotide Polymorphisms; Methods and Protocol Anton A. Komar Book 2009Latest edition Humana Press 2009 Advanced genome sequencing.A

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发表于 2025-3-21 17:48:39 | 显示全部楼层 |阅读模式
书目名称Single Nucleotide Polymorphisms
副标题Methods and Protocol
编辑Anton A. Komar
视频video
概述Fully updated from the first edition to offer cutting-edge methods for SNP detection and analysis.Offers a unique overview of next generation sequencing and genotyping approaches.Contains review chapt
丛书名称Methods in Molecular Biology
图书封面Titlebook: Single Nucleotide Polymorphisms; Methods and Protocol Anton A. Komar Book 2009Latest edition Humana Press 2009 Advanced genome sequencing.A
描述.In recent years, single nucleotide polymorphisms have received increased and special attention in a rapidly developing field of personalized medicine and drug treatment. Comprising more than eighty percent of all known polymorphisms, single nucleotide polymorphisms (SNPs) are primarily responsible for phenotypic differences between individuals, and have been suggested to affect the development of diseases in humans and the response to drug treatment and environmental stress. In .Single Nucleotide Polymorphisms: Methods and Protocols, Second Edition., expert researchers explore the latest advances in this area, highlighting the substantial progress that has been made in SNP genotyping, examining recent developments in high-throughput genotyping approaches, and exploring our new understanding of the impact of SNPs on gene function. Chapters address the impact of SNPs on phenotype, examine SNP databases, look at methods that have been applied for SNP bioinformatics discovery and analysis, and discuss advanced experimental approaches used for SNP detection. Composed in the highly successful .Methods in Molecular Biology.™ series format, each chapter contains a brief introduction, step
出版日期Book 2009Latest edition
关键词Advanced genome sequencing; Allele; DNA; DNA sequencing; Direct SNP detection; Indirect SNP detection; Iso
版次2
doihttps://doi.org/10.1007/978-1-60327-411-1
isbn_softcover978-1-61779-679-1
isbn_ebook978-1-60327-411-1Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2009
The information of publication is updating

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发表于 2025-3-21 23:50:35 | 显示全部楼层
Silent (Synonymous) SNPs: Should We Care About Them?olymorphisms can affect messenger RNA splicing, stability, and structure as well as protein folding. These changes can have a significant effect on the function of proteins, change cellular response to therapeutic targets, and often explain the different responses of individual patients to a certain
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Next-Generation Sequencing Methods: Impact of Sequencing Accuracy on SNP Discoveryt requirements for single nucleotide polymorphism (SNP) discovery utilizing these approaches is discussed along with a review of studies that have successfully employed next-generation sequencing methods for large-scale SNP discovery. Ultimately, the application of these ultra-high-throughput sequen
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Ryan Hunt,Zuben E. Sauna,Suresh V. Ambudkar,Michael M. Gottesman,Chava Kimchi-Sarfatyr, und zwar ohne eine Entlastungsmöglichkeit. Die Verjährung dieser Ansprüche tritt nach 30 Jahren ein. Auch wenn der klinisch tätige Arzt nicht selbst Vertragspartner wird, kann er für Schäden, die er zu verantworten hat, vom Krankenhausträger im Regreßwege in Anspruch genommen werden. Er muß darau
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onsmanagement vor den neuen gesetzlichen Bestimmungen vorgestellt. Angesichts der knapper gewordenen Ressourcen wird medizinisches Handeln in Zukunft vermehrt auch mit den Maßstäben der Effektivität und der Ökonomie gemessen werden müssen. Als Folge dieser Entwicklung sind medizinische Standards und Leitlinie978-3-642-47707-2978-3-642-47705-8
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