Titlebook: Single Cell Biomedicine; Jianqin Gu,Xiangdong Wang Book 2018 Springer Nature Singapore Pte Ltd. 2018 Biomedical Functions.Detection Target

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The Potential Roles and Advantages of Single Cell Sequencing in the Diagnosis and Treatment of Hemacer cells. SCS may also be able to monitor minimal residual disease (MRD) of HM by sequencing circulating tumor cells (CTCs) from peripheral blood. Functional heterogeneity and clonal evolution exist in acute leukemia, multiple myeloma (MM) and chronic myeloid leukemia (CML) subpopulations and have

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Is Pooled CRISPR-Screening the Dawn of a New Era for Functional Genomics,le-cell RNA-sequencing (scRNA-seq) and is the newest addition to the geneticist’s arsenal, providing scientists with methods to edit DNA with improved speed, accuracy, and efficiency which could usher us into a new era of study methods for functional genomics. We briefly overview the CRISPR-Cas9 sys

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Can the Single Cell Make Biomedicine Different?,nce of disease-associated single cell research, define the significance of single cell biomedicine in the pathogenesis of diseases, value the correlation of single cell gene sequencing with disease-specific biomarkers, and monitor the dynamics of RNA processes and responses to microenvironmental changes and drug resistances.

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Detection and Application of RNA Editing in Cancer,f carcinogenesis. In this review, we will discuss the main types of RNA editing and their role in cancers, as well as the current detection methods of RNA editing and the challenges we should overcome.

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Can the Single Cell Make Biomedicine Different?,r mechanisms of organ function and biology. The current issue with a special focus on single cell biomedicine is the first effort to collect the evidence of disease-associated single cell research, define the significance of single cell biomedicine in the pathogenesis of diseases, value the correlat

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Automated Single-Cell Analysis and Isolation System: A Paradigm Shift in Cell Screening Methods forg >10. cells, thus allowing the establishment of new cell screening methods for bio-medicines. In this chapter, an outline of the proposed automated single-cell analysis and isolation system (hereafter called ‘single-cell robot’) is reviewed by comparison with a conventional fluorescence-activated c

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High Throughput Single Cell RNA Sequencing, Bioinformatics Analysis and Applications,(NGS) technology is the driving force for single cell sequencing. scRNA-seq requires a lengthy pipeline comprising of single cell sorting, RNA extraction, reverse transcription, amplification, library construction, sequencing and subsequent bioinformatic analysis. Computational algorithms are essent

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