Titlebook: Signal Transduction in Cancer Metastasis; Wen-Sheng Wu,Chi-Tan Hu Book 2010 Springer Science+Business Media B.V. 2010 Activation.Cancer me

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Mitogen-Activated Protein Kinase-Activated Protein Kinases and Metastasis,s, motility, and tissue invasion. Signalling pathways, including the mitogen-activated protein kinase (MAPK) signalling pathways, regulate these cellular processes. Not unexpectedly, cancer cells display defects in signalling pathways due to mutations in genes encoding signal transduction proteins.

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Notch Signaling in Cancer Metastasis,pment, but also plays critical roles in the pathogenesis of human hematologic and solid malignancies. Notch has been shown to regulate cell proliferation, differentiation and apoptosis in a wide variety of cancer cells and recent studies have implicated Notch signaling in multiple aspects of tumor c

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