Titlebook: Sickle Cell Anemia; From Basic Science t Fernando Ferreira Costa,Nicola Conran Book 2016 Springer International Publishing Switzerland 2016

火光在摇曳

高原

Cardiovascular Adaptations to Anemia and the Vascular Endothelium in Sickle Cell Disease Pathophysixide, appear dysregulated and may also contribute to the vascular complications of sickle cell disease. The therapeutic potential of pharmacologically manipulating these molecules has not yet been achieved; however, evidence from patients treated with hydroxyurea and hematopoietic stem cell transpla

矛盾心理

intoxicate

Clinical Manifestations of Sickle Cell Anemia: Infants and Children,reased growth. Despite these many potential problems, with advances in care including antibiotic treatment, stroke screening, blood transfusions, and hydroxyurea therapy, children with SCD rarely die in childhood and can become productive adults.

Stress-Fracture

Treatment of Childhood Sickle Cell Disease,acute chest syndrome, acute splenic sequestration, cerebrovascular accidents, priapism, aplastic crisis, hepatobiliary complications and ophthalmologic complications. We also present approaches for chronic complications such as pulmonary hypertension, chronic kidney disease, chronic pain, sickle ret

袭击

ineluctable

Clinical Manifestations and Treatment of Adult Sickle Cell Disease,here is still room for improvement in the prevention, early diagnosis, and treatment of complications more frequently encountered by adult hematologists, and need for consultation with other subspecialties becomes a rule when caring for adult sickle cell patients. We review the clinical presentation

旁观者

休战

Sickle Cell Disease in Africa and the Arabian Peninsula: Current Management and Challenges,ing pictures in terms of the epidemiology, clinical presentation, management practices and the prevailing challenges. It looks at the peculiar issues of resource limitation in Africa and outlines strategies that could surmount some of the challenges. While most of the countries in the Arabian Penins

Brain-Waves

Future Perspectives for the Treatment of Sickle Cell Anemia,g., drugs that alter the hemoglobin oxygen affinity or enhance fetal hemoglobin production). “Downstream therapies” are those aimed at quelling the downstream effects of hemolysis and vaso-occlusion (e.g., anti-adhesive, anti-inflammatory, or vaso-dilatory agents). This chapter discusses new therapi