Titlebook: SialoGlyco Chemistry and Biology I; Biosynthesis, struct Rita Gerardy-Schahn,Philippe Delannoy,Mark von Itz Book 2015 Springer Internationa

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Book 2015s all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emergi

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CMP-Sialic Acid Synthetase: The Point of Constriction in the Sialylation Pathway,osynthesis of sialylated glycoconjugates is the activation of sialic acid to the monophosphate diester CMP-sialic acid. Only the activated sugar is transported into the Golgi apparatus and serves as a substrate for the linkage-specific sialyltransferases. Interference with sugar activation abolishes

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Structure and Function of Mammalian Sialidases,ytic reaction may greatly influence biological processes through changing the conformation of glycoproteins and create or mask binding sites of functional molecules. Recent progress in sialidase research has clarified that mammalian sialidases indeed contribute to the regulation of various cellular

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Functions and Biosynthesis of ,-Acetylated Sialic Acids,ganglioside-mediated apoptosis. Expression of .acetylated sialoglycans is regulated by sialic acid-specific .-acetyltransferases and .-acetylesterases. Recent developments in the identification of the enigmatic sialic acid-specific .acetyltransferase are discussed.

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Nanostructural Cell Wall Changes Due to Thermal Degradation in Woods of the nano-structural changes that take place during pyrolysis will inform fire models to ensure fire safety in timber structures. Here, small- and wide-angle x-ray scattering (SAXS/WAXS) based tomography were used to study how thermal degradation changes wood nanostructure across the pyrolysis z

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Cardiogenic Shockring intensive monitoring, aggressive hemodynamic support and tailored therapy according to the specific etiology. We describe a case of cardiogenic shock and its management of a patient with a dilated valvular cardiomyopathy.

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