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Titlebook: Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity; Franck Mauvais-Jarvis Book 2017 Springer International Publi

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发表于 2025-3-21 18:54:30 | 显示全部楼层 |阅读模式
书目名称Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
编辑Franck Mauvais-Jarvis
视频video
概述The first book to discuss gender biology and sex differences in endocrinology research and drug discovery for metabolic diseases.Expands on presentations and discussions at the March 2017 Keystone Sym
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity;  Franck Mauvais-Jarvis Book 2017 Springer International Publi
描述The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases..There are fundamental aspects of metabolic homeostasis that are regulated differently in males. and females, and influence boththe development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of
出版日期Book 2017
关键词sex differences; metabolism; adipose tissue; estrogen; androgen; gender medicine; andrology
版次1
doihttps://doi.org/10.1007/978-3-319-70178-3
isbn_softcover978-3-319-88897-2
isbn_ebook978-3-319-70178-3Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightSpringer International Publishing AG 2017
The information of publication is updating

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Sex Differences in Body Compositionose tissue around the trunk and abdomen, whereas women usually accumulate adipose tissue around the hips and thighs. Less is known about sex differences in ectopic fat depots. Advances in imaging allow the . assessment of abdominal and femorogluteal fat compartments, intramyocellular lipids, intrahe
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Men Are from Mars, Women Are from Venus: Sex Differences in Insulin Action and Secretiono the sex-related differences in glucose metabolism include differences in lifestyle (diet and exercise), sex hormones, and body composition. Several epidemiological and observational studies have noted that impaired glucose tolerance is more common in women than men. Some of these studies have attr
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Sex Differences in Leptin Control of Cardiovascular Function in Health and Metabolic Diseaseseted in a sex-specific manner. Although it has clearly been established that females secrete three to four times more leptin than males and that this sexual dimorphism in leptin secretion is exacerbated with overweight and obesity, the origin and the physiological consequences of this sexual dimorph
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Sex Differences in Muscle Wastingoxidative stress, mitochondrial dysfunction, satellite cell senescence, elevated apoptosis and proteasome activity, and suppressed protein synthesis and myocyte regeneration. Decreased food intake and physical activity also indirectly contribute to muscle wasting. Sex hormones also play important ro
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Origins and Functions of the Ventrolateral VMH: A Complex Neuronal Cluster Orchestrating Sex Differes. It is not surprising that hypothalamic nuclei play a pivotal role in controlling sex-dependent physiology. This brain region functions as a chief executive officer or master regulator of homeostatic physiological systems to integrate both external and internal signals. In this review, we describe
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