Titlebook: Serotonin; Ewan J. Mylecharane,James A. Angus,Patrick P. A. H Book 1989 Palgrave Macmillan, a division of Macmillan Publishers Limited 198

良心

anticipate

The Development of 5-HT3 Receptor Antagonists MDL 72222. Thus, of the other major contributors to the field (Table 2.1), the route to the development of ICS 205–930 at Sandoz has already been described (Richardson .., 1985); conversely, little or no information is available in this context for BRL 24924 and BRL 43694 (Beecham) and GR 38032F (G

nepotism

保守

doxazosin

Multiple 5-HT Receptors in the Enteric Nervous Systemric nervous system (ENS) was not appreciated, although many of the essential and distinguishing characteristics of that division of the autonomic nervous system (ANS) had already been published. The pioneering experiments of Bayliss and Starling (1899), ., and Trendelenburg (1917), ., established th

痛得哭了

5-HT Receptors Mediating Pre-synaptic Autoinhibition in Central Serotoninergic Nerve Terminalsthey can be activated by serotonin (5-hydroxytryptamine; 5-HT) released from those terminals on which they are located. It is compatible with this location that 5-HT autoreceptors probably play a physiological role in fine regulation of 5-HT release (and of 5-HT synthesis: Hamon .., 1973; Sawada and

paleolithic

切割

Electrophysiology of Receptors Mediating the Central Nervous System Actions of 5-Hydroxytryptamineonists and antagonists on peripheral tissues (Bradley .., 1986). To date, however, little is known about the nature of functional receptors on central neurones, although one of the earliest reports on the central effects of 5-HT reported the heterogeneity of neuronal responses to 5-HT (Roberts and S

环形

Neuronal Actions of 5-Hydroxytryptamine: An Overviewsion described excitatory and inhibitory actions, in the periphery and the CNS; all three of the recognized 5-HT receptor types may be involved, as is at least one other type. Particular aspects of the contributions in this session attracted much comment, as did some of the data presented in the pos

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