书目名称 | Sensory and Metabolic Control of Energy Balance |
编辑 | Wolfgang Meyerhof,Ulrike Beisiegel,Hans-Georg Joos |
视频video | |
概述 | Up-to-date account of the scientific progress made in the understanding of molecular mechanisms regulating energy metabolism.Special emphasis on obesity.Written by experts in the field.Includes supple |
丛书名称 | Results and Problems in Cell Differentiation |
图书封面 |  |
描述 | During the last two decades, the prevalence of obesity has dramatically increased in western and westernized societies. Its devastating health consequences include hypertension, cardiovascular diseases, or diabetes and make obesity the second leading cause of unnecessary deaths in the USA. As a consequence, obesity has a strong negative impact on the public health care systems. Recently emerging scienti?c insight has helped understanding obesity as a complex chronic disease with multiple causes. A multileveled gene–environment interaction appears to involve a substantial number of susceptibility genes, as well as associations with low physical activity levels and intake of high-calorie, low-cost, foods. Unfor- nately, therapeutic options to prevent or cure this disease are extremely limited, posing an extraordinary challenge for today’s biomedical research community. Obesity results from imbalanced energy metabolism leading to lipid storage. Only detailed understanding of the multiple molecular underpinnings of energy metabolism can provide the basis for future therapeutic options. Numerous aspects of obesity are currently studied, including the essential role of neural and endocri |
出版日期 | Book 2010 |
关键词 | Diabetes; Energy Balance; Insulin; Metabolism; Obesity; Regulation; cellular mechanisms; homeostasis; metabo |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-14426-4 |
isbn_softcover | 978-3-642-26518-1 |
isbn_ebook | 978-3-642-14426-4Series ISSN 0080-1844 Series E-ISSN 1861-0412 |
issn_series | 0080-1844 |
copyright | Springer-Verlag Berlin Heidelberg 2010 |