Titlebook: Sensing with Ion Channels; Boris Martinac Book 2008 Springer-Verlag Berlin Heidelberg 2008 Calcium.Ionenkanäle.Membrane, biologische.Signa

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Book 2008ste, smell or pain are essential to the survival of all living organisms. The importance of sensory input for the existence of life thus justifies the effort made to understand its molecular origins. Sensing with Ion Channels focuses on ion channels as key molecules enabling biological systems to se

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Microbial Senses and Ion Channels,early microbes long before the appearance of this complexity. Among such molecules are those that sense light, heat, force, water, and ligands. Though historically and didactically associated with the nervous system, ion channels also have deep evolutionary roots. For example, force sensing with cha

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Mechanosensitive Channels and Sensing Osmotic Stimuli in Bacteria,ces that are generated by even small changes in the osmolarity are massive. In response to increases in the osmolarity of the medium, also called osmotic upshock, the cell transports and synthesizes cytoplasmic osmoprotectants, which thus help to maintain its turgor. A subsequent severe osmotic down

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Roles of Ion Channels in the Environmental Responses of Plants,siently activated to convert these stimuli into intracellular signals. Among the ions taken up by plant cells, Ca. plays an essential role as an intracellular second messenger in plants; the cytoplasmic free Ca. concentration ([Ca.].) is therefore strictly regulated. Signal transduction pathways med

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Ion Channels, Cell Volume, Cell Proliferation and Apoptotic Cell Death,alterations of cell volume are accomplished by altered regulation of ion transport including ion channels. Thus, cell proliferation and apoptosis are both paralleled by altered activity of ion channels, which play an active part in these fundamental cellular mechanisms. Activation of anion channels

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TRPC Family of Ion Channels and Mechanotransduction,hannels. The MS functions of TRPCs may be mechanistically related to their better known functions as store-operated (SOCs) and receptor-operated channels (ROCs). In particular, mechanical forces may be conveyed to TRPC channels through “conformational coupling” and/or “Ca. influx factor” mechanisms

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Biophysics of CNG Ion Channels,fferent neurons and non-neuronal cells. This chapter will concentrate primarily on the biophysical aspects of retinal and olfactory CNG channels, with special reference to ion permeation and selectivity and their underlying molecular basis, and will include a brief overview of the physiological func