书目名称 | Self-Assembled Molecules – New Kind of Protein Ligands |
副标题 | Supramolecular Ligan |
编辑 | Irena Roterman,Leszek Konieczny |
视频video | |
概述 | An up-to-date account of supramolecular ligands.Essential reading for academic and industrial scientists interested in drug targeting.A comprehensive overview of the enhancement of immune complexation |
图书封面 |  |
描述 | .The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book. This book is an open access under a CC BY license. . |
出版日期 | Book‘‘‘‘‘‘‘‘ 2018 |
关键词 | Immunotargeting techniques; Ligands; Intramolecular Immunological Signals; Congo Red; Amyloids; Open Acce |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-65639-7 |
isbn_softcover | 978-3-319-88071-6 |
isbn_ebook | 978-3-319-65639-7 |
copyright | The Editor(s) (if applicable) and The Author(s) 2018 |