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Titlebook: Selective Toxicity; The physico-chemical Adrien Albert Book 1973Latest edition Adrien Albert 1973 research.therapy.toxicity

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Surface chemistry. The modification of membranes by surface-active agentstein membranes (see Section 4.1). It is now widely thought that life is possible only because of the presence of these biphasic membranes (lipophilic within, and hydrophilic on both outer surfaces), which provide for the separation of reactants. They also impose, on the sequence of reactions, an ord
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Chemotherapy: history and principleslly caused a given disease, made it possible for biologists to study infectious diseases experimentally for the first time. This set the scene for the discovery of chemotherapy, but it was slow to arrive as we shall see.
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Metabolites, enzymes, and metabolite analoguesg from a close resemblance between a normal substrate of an enzyme and an agent which inhibits it. Alternatively, the resemblance may be between the agent and a coenzyme. The products of the substrates can be referred to collectively as ..
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Biological activity unrelated to structure. Ferguson’s Principlethe substances used as hypnotics and general anaesthetics. High concentrations of depressants are also used as volatile insecticides, particularly in the fumigation of stored grain. The antimitotic effects mentioned in Section 15.1 are also evident at low concentrations and seem to be independent of structure.
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