Titlebook: Sedation and Analgesia for the Pediatric Intensivist; A Clinical Guide Pradip P. Kamat,John W. Berkenbosch Book 2021 Springer Nature Switze

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Alpha-Agonists in Pediatric Critical Careare unit (PICU) sedatives. Their mechanism of action produces a unique type of sedation which facilitates greater patient cooperation and, possibly, lighter levels of sedation to be tolerated. While two drug options are available, dexmedetomidine has become the most commonly used primary intravenous

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Sedation and Analgesia for the Critically Ill Child: KetamineNMDA) receptor antagonist, has been used for decades for its sedative and analgesic properties. In the pediatric intensive care unit (PICU), ketamine has been used for a variety of indications, commonly for procedural sedation. At subanesthetic doses, ketamine is also used for acute and chronic pain

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Propofol for Sedation of the Critically Ill Childd rapid offset. Its major dose-dependent side effects include respiratory depression and hypotension. It is frequently administered for procedural sedation and anesthesia in pediatrics, but its use as a continuous sedative infusion for critically ill children is limited by safety concerns, specifica

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Inhalational Agents: What Volatile Inhalational Agents Are and How to Use Them in the ICU Settinge anesthetics has expanded to the critical care setting. Patients admitted to the pediatric intensive care unit (PICU) from the emergency department (ED) or operating room often require continuous and prolonged infusions of sedatives and opioids for management of pain and anxiety, tolerance of mecha

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Neuromuscular Blockade for the Critically Ill Childrome, status asthmaticus, and increased intracranial hypertension. In this chapter, we discuss basic physiology of the neuromuscular junction and various neuromuscular blocking agents available in the PICU, as well as their basic pharmacology, dosing, monitoring, and adverse events.

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Sedation Considerations for Patients with Congenital and Acquired Heart Diseaseth heart disease are not only at risk from an airway perspective but also could be at risk for hemodynamic compromise due to cardiac issues. This chapter addresses basic pathophysiology of common congenital and acquired heart diseases and an approach to procedural sedation in this cohort.

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