Titlebook: Screening for Biological Response Modifiers: Methods and Rationale; James E. Talmadge,Isaiah J. Fidler,Robert K. Oldha Book 1985 Martinus

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James E. Talmadge Ph.D.,Isaiah J. Fidler D.V.M., Ph.D.,Robert K. Oldham M.D.

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James E. Talmadge Ph.D.,Isaiah J. Fidler D.V.M., Ph.D.,Robert K. Oldham M.D.

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Procedures for Preclinical Screening of Biological Response Modifying Agents,

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Screening for Biological Response Modifiers: Methods and Rationale978-1-4613-2591-8

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Preclinical Evaluation of Individual Biological Response Modifiers,ons directly affect both malignant and normal cells by slowing their cycling time. This was initially demonstrated with the L-1210 lymphoma, whose growth . as well as . can be inhibited by interferon. Thus, the antiproliferative effects of interferon may account for some of the antitumor effects obs

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Clinical Correlations,ewhat superfical nature. The BRMP is developing a unified approach to immunomonitoring during clinical trials and we hope that similar approaches will be established for most clinical trials. The Preclinical Screening Laboratory’and Biological Response Modifiers Program are undertaking a comprehensi

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