书目名称 | Scanning Ion Conductance Microscopy | 编辑 | Tilman E. Schäffer | 视频video | | 概述 | Overview of hot topics in scanning ion conductance microscopy (SICM).Presents recent applications of SICM and advantages over other techniques.Multi-authored volume with contributions from experts in | 丛书名称 | Bioanalytical Reviews | 图书封面 |  | 描述 | .This book provides a selection of recent developments in scanning ion conductance microscopy (SICM) technology and applications. In recent years, SICM has been applied in an ever-increasing number of areas in the bioanalytical sciences. SICM is based on an electrolyte-filled nanopipette with a nanometer-scale opening, over which an electric potential is applied. The induced ion current is measured, which allows to directly or indirectly quantify various physical quantities such as pipette-sample distance, ion concentration, sample elastic modulus among many others. This makes SICM well suited for applications in electrolytes - most prominently for the study of live cells..This book starts with a historic overview starting from the days of the invention of SICM by Paul Hansma at the University of California at Santa Barbara in 1989. SICM is a member of the family of scanning probe microscopies. It is related to another prominent member of the family, atomic force microscopy (AFM), which has found application in almost any field of nanoscale science. The advantages and disadvantages of SICM over AFM are also outlined. One of the most effective and break-through applications of SICM | 出版日期 | Book 2022 | 关键词 | scanning ion conductance microscopy (SICM); atomic force microscopy; Ion channel recording; smart patch | 版次 | 1 | doi | https://doi.org/10.1007/978-3-031-14443-1 | isbn_softcover | 978-3-031-14445-5 | isbn_ebook | 978-3-031-14443-1Series ISSN 1867-2086 Series E-ISSN 1867-2094 | issn_series | 1867-2086 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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