Titlebook: Safety in Cell and Tissue Culture; G. Stacey,A. Doyle,P. Hambleton Book 1998 Springer Science+Business Media Dordrecht 1998 biological mat

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John Benbough,B. Andrew Currankommen konnte und was Sie andererseits tun können, um diese zu meistern und dadurch Ihre außergewöhnlichen Gaben im Leben nutzbar zumachen. Die Autorin dieses Werkes ermutigt Sie über folgende Worte nachzudenken: Hochsensibilität ist Kompetenz!.978-3-662-53839-5978-3-662-53840-1

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Laboratory practice,atories. The use of such technology can be made safe by utilizing proper methods of containment, and good laboratory discipline, practice and procedures [1]. Legislation and guidelines issued by national regulatory bodies (e.g. COSHH UK [2], EEC [3], US Department of Health and Human Services [4], W

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Planning and design of a cell and tissue culture laboratory, biological culture under sterile conditions (monoseptic), particularly ensuring the absence of bacteria and fungi. The facilities therefore must reflect this unusual need in the nature of equipment and laboratory design. The ideal way to plan a tissue culture laboratory is to start from scratch wit

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Quality control and validation,ically acceptable and reproducible means of production in comparison with the use of animals and primary cells. Furthermore, mammalian cell lines have the potential to provide complex recombinant biologicals with post-translational modifications (i.e. glycosylation) which are typical of native glyco

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Containment facilities: design, construction and working practices,perator and environmental protection. Categorization of biological agents according to hazard and categories of containment is fully described in the ACDP guidelines [1]. For animal cell cultures, even where a pathogen has not been identified, the uncertainty arising from the potential for contamina

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Scale-up of animal cell culture systems,however it does significantly increase any risk. This is because with scale-up comes increased complexity of equipment and the process, thus greater risk of system failure leading either to contamination or potential release of hazardous materials. In addition the greater volumes of biological mater

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