| 书目名称 | SUMO Regulation of Cellular Processes | | 编辑 | Van G. Wilson | | 视频video | | | 概述 | Presents a unique compendium on sumoylation topics.Provides authoritative contributions from leading experts in the field of sumoylation.Expands on a previous edition with 6 new chapters | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | .This is the second edition of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule. .Individual chapters explore the biochemistry, molecular biology, and cell biology of the sumoylation system and its substrate proteins..The book is divided into three themed parts: Molecular Functions (I), Cell Growth Regulation (II), and Diseases (III). Parts I and II focus on the contribution of sumoylation to cellular activities in both the nuclear and cytoplasmic compartments. The nuclear activities covered include nucleic acid metabolism (both RNA and DNA), chromosome structure and replication, and nucleocytoplasmic transport. Cytoplasmic processes presented include regulation of membrane ion channels, general metabolism, and apoptotic signalling. Topics in Part III include the role of sumoylation in developmental abnormalities (craniofacial and cardiovascular), diabetes, neurodegenerative diseases, cancer, and infections with viruses and bacteria..E | | 出版日期 | Book 2017Latest edition | | 关键词 | DNA; Translation; cellular processes; molecular mechanisms; post-translational modification; regulation; S | | 版次 | 2 | | doi | https://doi.org/10.1007/978-3-319-50044-7 | | isbn_softcover | 978-3-319-84304-9 | | isbn_ebook | 978-3-319-50044-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | Springer International Publishing AG 2017 |
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发表于 2025-3-21 19:46:07
