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Titlebook: Ruhrkohlen-Handbuch; Ein Hilfsbuch für de Rheinisch-Westfälischen Kohlen-Syndikat Book 1937 Rheinisch-Westfälisches Kohlen-Syndikat, Essen

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Rheinisch-Westfälischen Kohlen-Syndikatogical and molecular heterogeneity (Anderson et al. 1998). They are relatively rare diseases, constituting <15 % of all NHL’s (Groves et al. 2000). The present 2008 WHO classification recognizes over 20 sub-types of mature T-cell and NK-cell malignancies (WHO 2008). These sub-types are listed in Tab
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Rheinisch-Westfälischen Kohlen-Syndikat characterized by uncontrolled proliferation and survival of clonal neoplastic lymphoid cells. Major breakthroughs in the past have contributed to our understanding of the genetic failures and the changed biology in lymphoma cells that underlie the initiation and progression of the disease. It is no
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Rheinisch-Westfälischen Kohlen-Syndikathis chromosomal abnormality as areciprocal translocation t(9;22)(q34;q1 1) by Rowley in 1973 (.), the identification of the genes involved at the translocation breakpoints (.,.), and ultimately the demonstration of the leukemogenic activity of the resulting fusion product (.), represent hallmarks fo
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and lymphomas (for a review, ..). These methodologies have provided powerful, robust, and precise characterizations of genetic mutations and gene rearrangements (both normal and abnormal) that have been applied to the diagnosis and treatment of these malignancies. In this chapter we discuss methodol
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