| 书目名称 | Rubidomycin | | 副标题 | A New Agent against | | 编辑 | J. Bernard,R. Paul,R. Maral | | 视频video | | | 丛书名称 | Recent Results in Cancer Research | | 图书封面 |  | | 描述 | Trials in the treatment of the leukemias are sometimes based on a hypothesis, as in the case of exchange transfusion [33] or the use of antimetabolites [86]. Or they are conducted empirically as the results of chance observations, as in the case of the use of the nitrogen mustards, urethane, and the Vinca alkaloids. Or they lie between the two, aiming at making use of well established biological facts: examples are the use of ACTH, cortisone and, more recently, the antibiotics. What is true for bacteria may also perhaps be true, if not for elephants, at least for the malignant cells of mammals. It was this idea that lay behind the first attempts at treating cancer and leukemia with antibiotics. The results obtained by the use of certain substances extracted from micro-organisms (actinomycin, azaserine, mito mycin, rufocromomycin), although encouraging at times, were inconsistent. The action of rubidomycin appears to cover a wider spectrum and to be more consistent and more effective. As in the case of Homer and Christopher Columbus, the honor of having given birth to rubidomycin is claimed by more than one country and town. In fact, the same product was discovered in the same year | | 出版日期 | Book 1969 | | 关键词 | alkaloids; antibiotics; cancer; leukemia | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-88125-1 | | isbn_softcover | 978-3-642-88127-5 | | isbn_ebook | 978-3-642-88125-1Series ISSN 0080-0015 Series E-ISSN 2197-6767 | | issn_series | 0080-0015 | | copyright | Springer-Verlag Berlin Heidelberg 1969 |
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发表于 2025-3-21 18:54:18
