| 书目名称 | Role of Autophagy and Reactive Oxygen Species in Cancer Treatment |
| 副标题 | Principles and Curre |
| 编辑 | Neeraj Mishra,Ravinder Kumar Kaundal |
| 视频video | |
| 概述 | Highlights the importance of autophagy and reactive oxygen species (ROS) in the treatment of cancer.Chapters cover recent accomplishments in the area, ranging from basic concepts to contemporary topic |
| 丛书名称 | Cancer Drug Discovery and Development |
| 图书封面 |  |
| 描述 | .Autophagy is a catabolic process that eliminates damaged and faulty cellular components via lysosomes. It responds to adverse circumstances like nutritional deficiency, hypoxia, and oxidative damage. Reactive oxygen species (ROS) cause oxidative stress, which is a multidimensional chemical that drives various pathophysiological diseases, including cancer. In addition, the autophagy process has a double role, first preventing tumour formation, but later fostering tumour progression. A growing body of research suggests that autophagy and ROS have a complex interplay in which they can either prevent cancer growth or enhance disease genesis. While a combination of autophagy inhibitor and cytotoxic medicines is now being used in cancer treatment, investigating the potential of autophagy inhibitors for overcoming resistance to different anticancer medications and how this relates to the control of cancer micro environmental stressors raises several questions. Autophagy‘s dual functions as a safeguarding and cytotoxic process have drawn attention to its significance in the development of cancer.. |
| 出版日期 | Book 2024 |
| 关键词 | Autophagy; Reactive Oxygen Species (ROS); Inflammation; Oxidative Stress; Tumor Metastasis; Tumor Progres |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-031-66421-2 |
| isbn_softcover | 978-3-031-66423-6 |
| isbn_ebook | 978-3-031-66421-2Series ISSN 2196-9906 Series E-ISSN 2196-9914 |
| issn_series | 2196-9906 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 18:50:42
