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Titlebook: Rodent Models of Stroke; Ulrich Dirnagl Book 2010 Springer Science + Business Media, LLC 2010 Brain and spinal cord injury.Focal cerebral

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书目名称Rodent Models of Stroke
编辑Ulrich Dirnagl
视频video
概述Provides hands-on guidance to most relevant stroke models in rodents.Comprehensive guide to non-invasive imaging in rodent stroke research (MRI, optical, nuclear medicine).Covers all relevant techniqu
丛书名称Neuromethods
图书封面Titlebook: Rodent Models of Stroke;  Ulrich Dirnagl Book 2010 Springer Science + Business Media, LLC 2010 Brain and spinal cord injury.Focal cerebral
描述In view of the numerous failures of clinical trials aimed at improving stroke therapy, the role and potential benefit of experimentally modeling focal cerebral ischemia in rodents has been debated. When methods of systematic review and metaanalyis are applied, however, it turns out that experimental models actually faithfully predicted the negative outcomes of clinical trials. In addition, thrombolysis and neuroprotection by hypothermia, first described in animal models, are key examples of treatment modalities that have made it successfully into clinical practice. In Rodent Models of Stroke, an international consortium of authors aims at critically addressing the issues on a very practical level, from choosing the model and outcome measures, designing the experiment, conducting and analyzing it, to reporting it in a scientific publication. The structure and content of the book reflect both the authors’ longstanding expertise in experimental and clinical stroke research and their roles in training the scientific community in the tools of the trade. As a volume in the successful Neuromethods series, the chapters provide authoritative reviews of the most commonly used, well-honed app
出版日期Book 2010
关键词Brain and spinal cord injury; Focal cerebral ischemia; Neurological injury; Neuroprotection; Stroke mode
版次1
doihttps://doi.org/10.1007/978-1-60761-750-1
isbn_softcover978-1-4939-5807-8
isbn_ebook978-1-60761-750-1Series ISSN 0893-2336 Series E-ISSN 1940-6045
issn_series 0893-2336
copyrightSpringer Science + Business Media, LLC 2010
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,Focal Cerebral Ischemia in the Mouse and Rat Using the Intraluminal Suture–Filament Model,
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Focal Ischemia Models: Middle Cerebral Artery Occlusion Induced by Electrocoagulation, Occluding De
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Photochemical and Endothelin Models of Focal Brain Ischemia,
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Noninvasive Brain Imaging in Small Animal Stroke Models: MRI and PET,
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Non-invasive Optical Imaging in Small Animal Models of Stroke,
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