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Titlebook: Risk/Benefit Analysis for the Use and Approval of Thrombolytic, Antiarrhythmic, and Hypolipidemic Ag; Proceedings of the N Joel Morganroth,

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New Agents and New Insights for Thrombolytic Therapy in Acute Myocardial Infarction: Focus on Anistr testing. Prourokinase is a fibrin-selective precursor form of urokinase undergoing initial trials both as a single agent and in combinations with urokinase and TPA. These agents expand the spectrum of thrombolytic options and may begin to impact clinical therapy in the near future.
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The Relative Benefit and Risks of Intravenous Streptokinase and Tissue Plasminogen Activator in Acutal infarction, Separate from the generic questions of patient selection criteria has been a sometimes acrimonious commercial issue-tinged debate concerning the relative risks and benefits to be expected following the use of one or the other of these two agents. Arguments center on questions of relat
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New Agents and New Insights for Thrombolytic Therapy in Acute Myocardial Infarction: Focus on Anistr anisoylated lys-plasminogen and streptokinase which is injected in a dose of 30 U over 2–5 min. Reperfusion rates of 60+10% and patency rates of 70–75% have been observed when it is given in <4 h. Mortality was reduced 48% after anistreplase in one study (AIMS). Intravenous urokinase has yielded re
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