| 书目名称 | Rise and Fall of Epithelial Phenotype | | 副标题 | Concepts of Epitheli | | 编辑 | Pierre Savagner | | 视频video | | | 概述 | Comprehensive and up-to-date.Detailed review of the field.Includes supplementary material: | | 丛书名称 | Molecular Biology Intelligence Unit | | 图书封面 |  | | 描述 | .Epithelial phenotype is a dynamic stage of differentiation that can be modulated during several physiological or pathological events. The rapid conversion to a mesenchymal-like phenotype is called an epithelial-mesenchymal transition (EMT). ..The .Rise and Fall of Epithelial Phenotype. is the first book to comprehensively introduce the concept of EMT. The first part of this volume describes main examples and models and explains their physiological relevance. These examples include hydra morphogenesis, gastrulation in mouse, drosophila and sea urchin, as well as neural crest cell migration and heart morphogenesis in vertebrates. Part two reviews in detail, specific EMT molecular pathways covering extracellular induction, transduction and transcription response and modulation of cell-cell adhesion structures. It emphasizes new specific pathways with potential medical applications. EMTs can also be linked to pathological events such as wound healing and cancer progression, as detailed in this section of the book.. | | 出版日期 | Book 2005 | | 关键词 | Drosophila; Gastrulation; Hydra; Vertebrate; carcinoma; migration; mouse; regulation; transcription | | 版次 | 1 | | doi | https://doi.org/10.1007/0-387-28671-3 | | isbn_softcover | 978-1-4419-3439-0 | | isbn_ebook | 978-0-387-28671-6Series ISSN 1431-0414 | | issn_series | 1431-0414 | | copyright | Springer-Verlag US 2005 |
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发表于 2025-3-21 18:39:06
