Titlebook: Reviews of Physiology, Biochemistry and Pharmacology Vol. 170; Bernd Nilius,Pieter de Tombe,Ole H. Petersen Book 2016 The Editor(s) (if ap

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0303-4240 opics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields..978-3-319-81051-5978-3-319-31492-1Series ISSN 0303-4240 Series E-ISSN 1617-5786

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Cardiac Response to Oxidative Stress Induced by Mitochondrial Dysfunction,oxidants have been tested and some are used clinically. In this review, we briefly discuss the role of mitochondrial DNA mutations, mitochondrial dysfunction, and ROS generation in the development of heart disease and recent developments in mitochondria-targeted antioxidants for the treatment of heart disease.

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Signature and Pathophysiology of Non-canonical Pores in Voltage-Dependent Cation Channels, essential physiological processes including shaping of action potentials and triggering Ca.-dependent processes. Classical textbooks describe the voltage-gated cation channels as membrane proteins with a single, central aqueous pore. In recent years, however, evidence has accumulated for the existe

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Cardiac Response to Oxidative Stress Induced by Mitochondrial Dysfunction,gy requirements, the heart is vulnerable to oxidative stress caused by the generation of endogenous reactive oxygen species (ROS). Therefore, the heart has effective regulatory and adaptive mechanisms to protect against oxidative stress. Inherited or acquired mitochondrial respiratory chain dysfunct

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I. Martín-Estal,R. G. de la Garza,I. Castilla-Cortázar

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Hyoung Kyu Kim,Bernd Nilius,Nari Kim,Kyung Soo Ko,Byoung Doo Rhee,Jin Han