Titlebook: Reviews of Physiology, Biochemistry and Pharmacology 154; S.G. Amara,E. Bamberg,M. Schweiger Book 2005 The Editor(s) (if applicable) and T

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Elucidation of mammalian bitter taste, linked to chromosomal loci known to influence bitter taste in mice and humans. The agonists for various TAS2Rs have been identified and all of them were established as bitter tastants. TAS2Rs are broadly tuned to detect multiple bitter substances, explaining, in part, how mammals can recognize nume

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Synaptic modulation in pain pathways,his system is essential to protect their bodies from tissue damage. However, under pathological conditions after severe tissue injury and in inflammatory or neuropathic diseases, this system can become sensitized, and pain can then turn into a disease. Such exaggerated pain sensation (or hyperalgesi

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The vertebrate phototransduction cascade: amplification and termination mechanisms,gnaling pathway called phototransduction. Works from psychophysicists, electrophysiologists, biochemists, and geneticists over several decades have come together to shape our understanding of how photon absorption leads to photoreceptor membrane hyperpolarization. The insights of phototransduction p

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