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Titlebook: Retinoid Therapy; A review of clinical W. J. Cunliffe,A. J. Miller Book 1984 MTP Press Limited 1984 therapy

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发表于 2025-3-21 19:54:08 | 显示全部楼层 |阅读模式
书目名称Retinoid Therapy
副标题A review of clinical
编辑W. J. Cunliffe,A. J. Miller
视频video
图书封面Titlebook: Retinoid Therapy; A review of clinical W. J. Cunliffe,A. J. Miller Book 1984 MTP Press Limited 1984 therapy
描述The impact of the retinoids in clinical practice has primarily been in dermatology. When Dr Werner Bollag began his basic research and screening programme in the early 1960‘s, the expectation was that the retinoids would have a major impact on oncology. However, the laboratory and clinical experiences of Bollag and his colleagues in Switzerland, Stuttgen and Orfanos in Germany, led to publications on both etretinates (Tigason) and isotretinoin (Roaccutane) in the years between 1972 and 1976 in the field of dermatology. In fact the first symposium on retinoid research held in Berlin in 1981 was almost entirely dermatological. A year later a retinoid workshop in Iowa was designed to provide a forum for dermatolog­ ists from the USA involved in specific protocols investigating oral retinoids. In the UK, research into the retinoids began rather later than in Continental Europe or in the USA, although Tigason was first marketed here. It was felt in late 1982 that as many dermatologists had relatively little experience with these compounds it would be appropriate to hold an International Symposium on retinoid therapy in the UK. Thus on 16-18 May 1983 in London, 37 speakers from 11 countr
出版日期Book 1984
关键词therapy
版次1
doihttps://doi.org/10.1007/978-94-011-6349-1
isbn_softcover978-94-011-6351-4
isbn_ebook978-94-011-6349-1
copyrightMTP Press Limited 1984
The information of publication is updating

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The Development of Retinoids in DermatologyThe retinoids are a class of compounds comprising both the natural forms and the synthetic analogues of vitamin A.
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Etretinate Treatment in Erosive Lichen Planus of the Oral Mucosaive gingivitis cause considerable discomfort. Unlike the cutaneous form, involvement of the oral mucosa tends to be prolonged, lasting for many years. Whereas some patients have concurrent lesions on the skin and oral mucosa, the majority appear to be restricted to one or other of these sites.
发表于 2025-3-22 18:23:42 | 显示全部楼层
Effects of Synthetic Retinoids on Human Peripheral Blood Lymphocytes and Polymorphonuclears ,yriasis rubra pilaris, etc. In these conditions, the site of action of retinoids seems to focus on the pathologically keratinizing epidermis. A large number of disorders of keratinization (DOK) of the skin showing ortho- or para-keratosis appear to respond to oral retinoids.
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The Effect of Etretinate on Chemotactic Activity of Polymorphonuclear Leukocytes in Various Forms ofding in the stratum corneum (Munro microabscesses) in fully developed lesions, and appear also in the corium of earliest psoriatic papules.. Increased activity of PMNs in psoriasis, as measured by Chemotaxis assay,. enzyme level,. superoxide anion production,. and enhanced adherence favour their direct involvement in the formation of skin lesions.
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