Titlebook: Retinal Degenerations; Biology, Diagnostics Joyce Tombran-Tink,Colin J. Barnstable Book 2007 Humana Press 2007 aging.apoptosis.biology.cell

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d new methods for quantification.Presents cell-based therapiFor centuries, humans have tried to explain the complex process of vision and find effective treatments for eye diseases. Perhaps the oldest surviving record of ancient ophthalmic practices is the Babylonian code of Hammurabi that over 4000

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Epidemiology of Age-Related Macular Degeneration Early in the 21st Century will remain a major threat to vision in coming decades (.,.). AMD research has progressed substantially in the last quarter of the 20th century and provides clues for future research directions (.,.–.). Although the exact etiology of AMD remains uncertain (.), we now have a considerably better unde

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Stargardt Diseasesal gene for autosomal recessive Stargardt disease (arSTGD or STGD1) (.) it seemed as if just another missing link was added to the extensive table of genetic determinants of rare monogenic retinal dystrophies. Now, 9 yr later, the . gene continues to emerge as the predominant determinant of a wide

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X-Linked Juvenile Retinoschisisof the more frequently inherited retinal disorders affecting macular function in males. The prevalence of RS has been estimated to range between 1 in 5000 to 1 in 20,000 (.). The name derives from an internal splitting of the retina mostly affecting the temporal periphery of the fundus. This trait i

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Mouse Models of RPn RP causes the degeneration of photoreceptor cells in the retina. As these cells degenerate and die, patients experience progressive vision loss to eventual blindness. The most common feature of all forms of RP is a gradual degeneration of photoreceptor cells: rod cells and cone cells. The rods and

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