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Titlebook: Restless Legs Syndrome/Willis Ekbom Disease; Long-Term Consequenc Mauro Manconi,Diego García-Borreguero Book 2017 Springer Science+Business

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发表于 2025-3-25 04:36:14 | 显示全部楼层
Treatment Options When Short-Acting Dopamine Agonists Fail or Cause Augmentation: Switching or Addinr add other therapy to control their RLS symptoms. This chapter discusses the different reasons for treatment failure and the various options for managing them. Guidelines include a revised algorithm for dealing with augmentation from short-acting dopamine agonists.
发表于 2025-3-25 08:07:13 | 显示全部楼层
RLS/WED: Criteria, Differential Diagnosis and Prevalence of Occurrence,underlined by epidemiological studies showing that one in 100 people may experience RLS/WED symptoms which seriously impact quality of life [.]. The diagnosis is based primarily on patient self-report and history. However, a number of diseases have symptoms that are often confused with those of RLS/
发表于 2025-3-25 13:06:07 | 显示全部楼层
Mental Health Disorders Associated with RLSded as a unique sleep disorder in the recent Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Epidemiological data from both population and clinic-based studies have found a higher incidence of mental illness—particularly depressive and anxiety disorders—among coho
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Cognitive Functioningestless legs syndrome (WED/RLS). These studies included acute, single-night treatments with levodopa, clonazepam, ropinirole, and gabapetin and prolonged treatment with pramipexole, gabapentin enacarbil. Methodological concerns, the low number of available studies and heterogeneity of results impede
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Health-Related Quality of Life and Depression Symptom Measures for the Assessment of Treatment in Reial well-being are affected by a medical condition or its treatment” (Cella in Semin Oncol 22:73–81, 1995 [.]). Individual patients with the same objective health status can report dissimilar HRQoL due to unique differences in expectations and coping abilities and it must be measured from the indivi
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Heart Rate and Blood Pressure Changes Associated with Periodic Limb Movementsiated with a higher degree of autonomic activation. PLMS are also known to be associated with statistically significant transient rises in systolic and diastolic blood pressure (BP). Such repetitive abnormal HR and BP rises can play a role in increased cardiovascular risk in restless legs syndrome (
发表于 2025-3-26 16:23:06 | 显示全部楼层
Willis–Ekbom Disease, Periodic Limb Movements of Sleep, and Cardiovascular Disease: Putative Mechanirelationship(s) mediating this association remain to be fully defined. In particular, it may be speculated that WED (or its associated periodic limb movements of sleep) is causal to CVD, that a common pathogenic feature or intermediate risk factor is causal to both WED and CVD, or that clinical or s
发表于 2025-3-26 20:27:19 | 显示全部楼层
Peripheral Muscle Changesrs. To provide adequate blood flow to the muscle, there should be a balance between the activity of vasoconstriction and vasodilatation. An imbalance favoring a vasoconstriction might induce local hypoxia. In restless leg syndrome (RLS) patients, there may be an imbalance between vasoconstriction an
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