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Titlebook: Respiratory Disease; Anne E. Tattersfield,Martin W. McNicol Textbook 1987 Springer-Verlag Berlin Heidelberg 1987 asthma.chemotherapy.defen

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Theophylline and Related Xanthines, plant. Theophylline was extracted from tea leaves in 1888, its formula identified in 1895 and its bronchodilator action in animals established early this century. Although its potential value as a bronchodilator for asthma was noted in 1921, it was not evaluated systematically until the late 1930s when it came into more general use.
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Sympathomimetic Amines,in 1967 were able to subdivide β-receptors into β.- and β.-adrenoceptors and to show that β.-receptor stimulation was responsible for bronchodilatation. This paved the way for the introduction of more β.-selective sympathomimetic amines in the 1960s.
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1431-9772 o each of the main respiratory diseases with particular emphasis on management and treatment. The second reviews the main drugs used in respiratory practice in more detail and combines a pharmacological appraisal with a more personal assessment of their role and value in treatment. Practical aspects
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Autonomic Control of Airway Function,The sympathetic and parasympathetic limbs of the autonomic nervous system modulate many aspects of lung function: airway and vascular smooth muscle tone, mucus secretion, surfactant production, ion transport, and release of mediators from resident cells such as mast cells.
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Antimuscarinic Drugs,Atropine and ipratropium bromide are anticholinergic drugs which act by com­petitive inhibition of acetylcholine at parasympathetic muscarinic receptors. Antagonism at nicotinic receptors is only seen with very high doses.
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Corticosteroids,Naturally occurring steroids consist of glucocorticoids affecting glucose metabolism and having associated anti-inflammatory activity, mineralocorticoids acting predominantly on renal handling of salt and water, and sex hormones.
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https://doi.org/10.1007/978-1-4471-3132-8asthma; chemotherapy; defence mechanisms; diseases; drug; drugs; infections; lung; medicine; pharmacology; res
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