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Titlebook: Research in Computational Molecular Biology; 9th Annual Internati Satoru Miyano,Jill Mesirov,Michael Waterman Conference proceedings 2005 S

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Consensus Folding of Unaligned RNA Sequences Revisitedacted attention again, thanking to the recent discoveries of many novel non-coding RNA molecules. The two common approaches to this problem are . prediction of RNA secondary structure based on energy minimization and “consensus folding” approach (computing the common secondary structure for a set of
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Discovery and Annotation of Genetic Modulesess information, to respond and adapt to an environment in fugue, is directly related to the combinatorially large number of ways genes can be selected and modulated to express its phenotypic repertoire. Viewed in this way it is clear that a cell lacks a fixed network structure, but instead has the
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Efficient ,-Gram Filters for Finding All ,-Matches over a Given Lengthhes between two sequences, i.e. all local alignments over a given length with an error rate of at most .. We study this problem theoretically, giving an efficient .-gram filter for solving it. Two applications of the filter are also discussed, in particular genomic sequence assembly and .-like seque
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A Fundamental Decomposition Theory for Phylogenetic Networks and Incompatible Charactersne of the most important of these biological operations is recombination between two sequences (homologous chromosomes). The algorithmic problem of reconstructing a history of recombinations, or determining the minimum number of recombinations needed, has been studied in a number of papers [10, 11,
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