Titlebook: Research in Computational Molecular Biology; 21st Annual Interna S. Cenk Sahinalp Conference proceedings 2017 Springer International Publi

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Conference proceedings 2017ina, in May 2017.. The 22 regular papers presented in this volume were carefully reviewed and selected from 184 submissions. 16 short abstracts are included in the back matter of the volume. They report on original research in all areas of computational molecular biology and bioinformatics

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Boosting Alignment Accuracy by Adaptive Local Realignment,ew method of ., when combined with prior methods for global advising, boosts alignment accuracy as much as 26% over the best default setting on hard-to-align protein benchmarks, and by 6.4% over global advising alone. Adaptive local realignment, implemented within the . aligner using the . accuracy estimator, is available at ..

低三下四之人

A Bayesian Active Learning Experimental Design for Inferring Signaling Networks, and selects interventions that maximize their expected contribution to structure learning. Evaluations on simulated and real data show that the strategy reduces the detection error of validated edges as compared to an unguided choice of interventions, and avoids redundant interventions, thereby increasing the effectiveness of the experiment.

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AllSome Sequence Bloom Trees,mption during queries. Notably, it can query a batch of 198,074 queries in under 8 h (compared to around two days previously) and a whole set of .-mers from a sequencing experiment (about 27 mil .-mers) in under 11 min.

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含水层

Christopher Pockrandt,Marcel Ehrhardt,Knut Reinert

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enhance and regulate a gene therapy or vice versa. Such combined approaches can hence increase the specificity and efficiency of the final therapy which may be much better than the individual ones. There are many hurdles to such dual-modality processes and hence must be employed after careful evalu

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