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Titlebook: Research in Computational Molecular Biology; 23rd Annual Internat Lenore J. Cowen Conference proceedings 2019 Springer Nature Switzerland A

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楼主: damped
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ents in novel receptor/liposome-based transfection systems have made nonviral gene therapy a real possibility. Described here is a novel, high-efficiency, nonviral protocol for delivery of genes into permeabilized primary cultured cells forming a first step toward ex vivo gene therapy for the repair
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Fatemeh Almodaresi,Prashant Pandey,Michael Ferdman,Rob Johnson,Rob Patro Injury to the alveolar-capillary barrier and lung inflammation lead to intrapulmonary shunting of blood, surfactant depletion, and pulmonary vascular obstruction. Although the exact incidence of ARDS is unknown, there is little doubt that tens of thousands of patients develop this syndrome annually
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Aryan Arbabi,David R. Adams,Sanja Fidler,Michael Brudnoyriad of endovascular or inhaled toxins, a series of temporally and spatially overlapping injury and repair events all too often result in a dysfunctional fibrotic lung. The fibroproliferative phase of acute lung injury is characterized by progressive accumulation of interstitial and alveolar myofib
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Chirag Jain,Haowen Zhang,Yu Gao,Srinivas Aluru the target cancer cells and high transduction of nontarget normal organs. To address these issues, we have been working on “retargeting” of Ad vectors via transductional or transcriptional targeting. Transductional targeting has been achieved with application of various bridging moieties, genetical
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Mikhail Karasikov,Harun Mustafa,Amir Joudaki,Sara Javadzadeh-No,Gunnar Rätsch,André Kahlesled to identify a suitable virus, which though unable to cause disease, retained the capability to replicate in cancer cells. In principal, the productive growth of the virus would kill or lyse malignant cells and the newly minted viral progeny would spread the infection, resulting ultimately in the
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