Titlebook: Reproductive Processes and Contraception; Kenneth W. McKerns Book 1981 Plenum Press, New York 1981 Gonadotropin.endocrinology.hormone.prot

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Regulation of LH-RH Secretion by Gonadal Steroids and Catecholamines960). A great deal of effort was directed toward the purification and chemical identification of the hypothalamic LH-releasing hormone (LH-RH). Matsuo .. (1971) characterized the chemical structure of the naturally occurring LH-RH and showed it to be biologically and chemically identical with the sy

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Antifertility Effects of LH-RH and Its Agonists for the treatment of male and female infertility. This application, which theoretically coincides with the profertility LH-re­leasing role played by endogenous LH-RH, has been and continues to be exhustively pursued, but use of the chemically and biologically identical synthetic LH-RH in a variety

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Stable and Specific Tracersrs has become increasingly widespread. The progestin receptor is now rarely assayed with labeled progesterone, but with radioligands such as [.H]promegestone (Duffy and Duffy, 1979; McGuire .., 1977b; Horwitz and McGuire, 1975; Philibert and Raynaud, 1973, 1974a, b) and [.H]-ORG 2058 (Keightley, 197

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Specific Inhibitors of Androgen Binding to the Androgen-Binding Protein (ABP)ues (Table I). Following binding of testosterone secreted by the Leydig cells on luteinizing hormone stimulation, ABP reaches, via the seminiferous tubules, the epididymis, beyond which it disappears (French and Ritzén, 1973; Hansson .., 1974). It has been suggested that ABP serves as an androgen-co

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Hormonal Modulation of Progesterone Receptorsley, 1976; Chan and O’Malley, 1976; DeLuca, 1979; Gorski and Gannon, 1976; Yamamoto and Alberts, 1976). There is general, but not universal, agreement that the hormone diffuses passively through the cell membrane (Baulieu, 1978). After entering the target cell, the hormone binds to a cytoplasmic rec